Epigenetics

DNA methylation is an epigenetic mechanism used by higher eukaryotes and involved in e.g. gene expression, X-Chromosome inactivating, imprinting, and gene silencing of germline specific gene and repetitive elements.

Requirements

Before diving into this topic, we recommend you to have a look at:

Material

You can view the tutorial materials in different languages by clicking the dropdown icon next to the slides () and tutorial () buttons below.
Lesson Slides Hands-on Recordings Input dataset Workflows
ATAC-Seq data analysis
CUT&RUN data analysis
DNA Methylation data analysis
Formation of the Super-Structures on the Inactive X
ChIP-seq
Hi-C analysis of Drosophila melanogaster cells using HiCExplorer
Identification of the binding sites of the T-cell acute lymphocytic leukemia protein 1 (TAL1)
ChIP-seq
Infinium Human Methylation BeadChip
Introduction to ChIP-Seq data analysis
Introduction to DNA Methylation data analysis

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Editorial Board

This material is reviewed by our Editorial Board:

orcid logoLucille Delisle avatar Lucille Delisleorcid logoFlorian Heyl avatar Florian HeylJoachim Wolff avatar Joachim Wolff

Contributors

This material was contributed to by:

orcid logoKhaled Jum'ah avatar Khaled Jum'ahorcid logoBjörn Grüning avatar Björn Grüningorcid logoKrzysztof Poterlowicz avatar Krzysztof Poterlowiczorcid logoMo Heydarian avatar Mo Heydarianorcid logoFlorian Heyl avatar Florian Heylorcid logoMallory Freeberg avatar Mallory FreebergTorsten Houwaart avatar Torsten Houwaartorcid logoMaria Doyle avatar Maria Doyleorcid logoLucille Delisle avatar Lucille Delisleorcid logoSaskia Hiltemann avatar Saskia Hiltemannorcid logoPavankumar Videm avatar Pavankumar Videmorcid logoBérénice Batut avatar Bérénice Batutorcid logoHelena Rasche avatar Helena RascheNiall Beard avatar Niall BeardVivek Bhardwaj avatar Vivek Bhardwajorcid logoWolfgang Maier avatar Wolfgang Maierorcid logoNicola Soranzo avatar Nicola SoranzoEkaterina Polkh avatar Ekaterina Polkhorcid logoKatarzyna Kamieniecka avatar Katarzyna KamienieckaMehmet Tekman avatar Mehmet TekmanFidel Ramirez avatar Fidel RamirezFriederike Dündar avatar Friederike Dündarorcid logoAnika Erxleben avatar Anika ErxlebenAnup Kumar avatar Anup KumarJoachim Wolff avatar Joachim Wolfforcid logoYvan Le Bras avatar Yvan Le BrasMélanie Petera avatar Mélanie PeteraLeily Rabbani avatar Leily RabbaniDevon Ryan avatar Devon Ryan

Funding

These individuals or organisations provided funding support for the development of this resource

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UFR
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CRC992
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ELIXIR Europe
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de.NBI