Epigenetics

DNA methylation is an epigenetic mechanism used by higher eukaryotes and involved in e.g. gene expression, X-Chromosome inactivating, imprinting, and gene silencing of germline specific gene and repetitive elements.

Requirements

Before diving into this topic, we recommend you to have a look at:

Material

You can view the tutorial materials in different languages by clicking the dropdown icon next to the slides () and tutorial () buttons below.
Lesson Slides Hands-on Recordings Input dataset Workflows
ATAC-Seq data analysis
CUT&RUN data analysis
DNA Methylation data analysis
Formation of the Super-Structures on the Inactive X
ChIP-seq
Hi-C analysis of Drosophila melanogaster cells using HiCExplorer
Identification of the binding sites of the T-cell acute lymphocytic leukemia protein 1 (TAL1)
ChIP-seq
Infinium Human Methylation BeadChip
Introduction to ChIP-Seq data analysis
Introduction to DNA Methylation data analysis

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Editorial Board

This material is reviewed by our Editorial Board:

orcid logoLucille Delisle avatar Lucille Delisleorcid logoFlorian Heyl avatar Florian HeylJoachim Wolff avatar Joachim Wolff

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Contributors

This material was contributed to by:

orcid logoNicola Soranzo avatar Nicola SoranzoNiall Beard avatar Niall Beardorcid logoHans-Rudolf Hotz avatar Hans-Rudolf HotzFriederike Dündar avatar Friederike DündarLeily Rabbani avatar Leily Rabbaniorcid logoAnika Erxleben avatar Anika Erxlebenorcid logoWolfgang Maier avatar Wolfgang MaierGildas Le Corguillé avatar Gildas Le CorguilléAnup Kumar avatar Anup Kumarorcid logoMo Heydarian avatar Mo HeydarianDevon Ryan avatar Devon Ryanorcid logoMallory Freeberg avatar Mallory Freebergorcid logoBjörn Grüning avatar Björn GrüningWilliam Durand avatar William Durandorcid logoYvan Le Bras avatar Yvan Le BrasMehmet Tekman avatar Mehmet Tekmanorcid logoKatarzyna Kamieniecka avatar Katarzyna Kamienieckaorcid logoSaskia Hiltemann avatar Saskia Hiltemannorcid logoKrzysztof Poterlowicz avatar Krzysztof Poterlowiczorcid logoLucille Delisle avatar Lucille DelisleTorsten Houwaart avatar Torsten HouwaartVivek Bhardwaj avatar Vivek Bhardwajorcid logoHelena Rasche avatar Helena RascheVerena Moosmann avatar Verena Moosmannorcid logoKhaled Jum'ah avatar Khaled Jum'ahorcid logoArmin Dadras avatar Armin DadrasMélanie Petera avatar Mélanie PeteraJoachim Wolff avatar Joachim Wolfforcid logoPavankumar Videm avatar Pavankumar Videmorcid logoFlorian Heyl avatar Florian Heylorcid logoMartin Čech avatar Martin Čechorcid logoTristan Reynolds avatar Tristan Reynoldsorcid logoCristóbal Gallardo avatar Cristóbal Gallardoorcid logoBérénice Batut avatar Bérénice BatutEkaterina Polkh avatar Ekaterina PolkhFidel Ramirez avatar Fidel Ramirezorcid logoMaria Doyle avatar Maria Doyle

Funding

These individuals or organisations provided funding support for the development of this resource

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CRC992
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ELIXIR Europe
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UFR
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de.NBI
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The University of Melbourne
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Australian BioCommons
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Melbourne Bioinformatics